Verified ComparisonLast updated: 20 April 2026
Mod GRF 1-29 vs Sermorelin
Sermorelin is the unmodified GHRH(1-29) sequence. Mod GRF 1-29 is a tetrasubstituted analog with extended half-life and potency.
Mod GRF 1-29
GH Releasing
4.3/ 5
A−
Sermorelin
GH Releasing
4.0/ 5
B+
Editor's note
Mod GRF 1-29 has higher stability; sermorelin is the parent compound with FDA approval history.
| Criterion | Mod GRF 1-29 | Sermorelin |
|---|---|---|
| Chemical modification | Tetrasubstituted | Native sequence |
| Stability in vivo | Higher | Lower |
| Potency per dose | Higher | Lower |
| FDA/regulatory history | Investigational | Approved (older), now discontinued |
| Research use frequency | Growing | Established in older studies |
Frequently asked questions
Enhanced stability and potency allow lower and fewer doses for equivalent GH stimulation.
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