Verified Peptide ReviewLast reviewed: 22 March 2026
Compound Profile · Growth Hormone
IGF-1 LR3
IGF-1 LR3 is a synthetic long-acting analog of insulin-like growth factor 1, studied in research for anabolic effects on muscle and tissue.
LegalResearch onlyEvidenceEmergingHuman useNot approved
6.8/ 10
Peptide Score
Evidence
Safety
Regulatory
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Quick verdict
Mechanistically potent but with significant systemic effects. Human evidence is limited and safety profile is not well-characterised.
Reality check
What this isn't
- Not approved for human use — research-only context
- No regulator has approved human use
- Evidence base is early — long-term data limited
- Side-effect profile not fully characterised
- Educational only — not medical advice
Full IGF-1 LR3 review
A 70-amino-acid peptide that is a modified form of human IGF-1 with an extended half-life (LR3 = long-acting).
It binds IGF-1 receptors systemically, affecting muscle, liver, pancreas and other tissues.
Looking at alternatives?
Compounds with comparable research interest but different evidence, regulatory status, or risk profile.