Verified Peptide ReviewLast reviewed: 22 February 2026
Compound Profile · Cosmetic
Melanotan II
Melanotan II is a synthetic melanocortin analog studied for its effects on pigmentation and erectile function. Safety concerns are substantial.
LegalResearch onlyEvidenceInsufficientHuman useNot approved
5.2/ 10
Peptide Score
Evidence
Safety
Regulatory
Transparency
Quick verdict
Often discussed for cosmetic effects. Safety signals — including reports of melanoma in users — make this a peptide we score low on safety clarity.
Reality check
What this isn't
- Not approved for human use — research-only context
- No regulator has approved human use
- Insufficient human evidence
- Side-effect profile not fully characterised
- Educational only — not medical advice
Full Melanotan II review
A non-selective melanocortin receptor agonist.
Looking at alternatives?
Compounds with comparable research interest but different evidence, regulatory status, or risk profile.