PEPTIDE
Verified Peptide ReviewLast reviewed: 30 March 2026

Compound Profile · Cognitive

Semax

Semax is a synthetic heptapeptide developed in Russia, studied for nootropic, anxiolytic and neuroprotective effects.

LegalResearch onlyEvidenceEmergingHuman useNot approved
6.8/ 10

Peptide Score

Evidence

6.4

Safety

7.6

Regulatory

6.8

Transparency

6.8

Quick verdict

Reported neuroprotective effects in Russian and some Asian trials. Western clinical evidence is limited.

Reality check

What this isn't

  • Not approved for human use — research-only context
  • No regulator has approved human use
  • Evidence base is early — long-term data limited
  • Side-effect profile not fully characterised
  • Educational only — not medical advice

Deep dive

Full Semax review

A synthetic peptide fragment derived from ACTH (adrenocorticotropic hormone).

Studied for effects on cognition, mood, neuroprotection and stress resilience.

CompareResearch-gradeSafety