Verified ComparisonLast updated: 2 April 2026
IGF-1 LR3 vs CJC-1295 + Ipamorelin
IGF-1 LR3 provides long-acting, direct IGF-1 signalling. CJC-1295 + ipamorelin stimulates endogenous GH through GHRH and ghrelin pathways.
IGF-1 LR3
Growth Hormone
4.3/ 5
A−
CJC-1295 + Ipamorelin
Growth Hormone
4.4/ 5
A
Editor's note
IGF-1 LR3 is direct but systemic; dual peptides stimulate endogenous GH release.
| Criterion | IGF-1 LR3 | CJC-1295 + Ipamorelin |
|---|---|---|
| Mechanism | Direct IGF-1 analog | Endogenous GH stimulation (GHRH + GHS-R) |
| Route | Subcutaneous injection | Subcutaneous injection |
| Half-life | Very long | Varies (long GHRH, short GHS) |
| Systemic IGF-1 exposure | Direct and sustained | Endogenous, pulsatile |
| GH axis stimulation | Suppressed (feedback) | Stimulated (dual-pathway) |
| Research literature depth | Moderate | Extensive |
Frequently asked questions
Dual GH-axis peptides stimulate endogenous release; IGF-1 LR3 provides direct, sustained exposure.
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