PEPTIDE
Verified ComparisonLast updated: 18 April 2026

Ipamorelin vs Mod GRF 1-29

These peptides target synergistic GH-release mechanisms. Ipamorelin binds GHRP receptors; Mod GRF 1-29 stimulates GH via GHRH.

Compound A

Ipamorelin

GH Secretagogue

Evidence
4.3/ 5
A−

Compound B

Mod GRF 1-29

GH Releasing

Evidence
4.2/ 5
A−
Editor's note
Ipamorelin acts on ghrelin pathway; Mod GRF 1-29 on GHRH pathway. Often combined in research.
CriterionIpamorelinMod GRF 1-29
MechanismGhrelin-receptor agonistGHRH analog
GH release pathwaySecretagogueSecretagogue-releasing
Synergistic potentialYes (with GHRH)Yes (with secretagogues)
Cortisol elevationMinimalMinimal
Research popularity combinedVery highVery high

Frequently asked questions

They stimulate GH via distinct pathways, allowing multiplicative effects in research protocols.