PEPTIDE
Verified Peptide ReviewLast reviewed: 18 February 2026

Compound Profile · Longevity

Epitalon

Epitalon (or Epithalon) is a synthetic tetrapeptide based on epithalamin, a pineal gland peptide. Most published work originates from a single research lineage.

LegalResearch onlyEvidenceEmergingHuman useNot approved
6.8/ 10

Peptide Score

Evidence

6.0

Safety

7.2

Regulatory

6.8

Transparency

7.2

Quick verdict

Frequently cited in longevity discussion but the published evidence base is narrower than the conversation suggests.

Reality check

What this isn't

  • Not approved for human use — research-only context
  • No regulator has approved human use
  • Evidence base is early — long-term data limited
  • Side-effect profile not fully characterised
  • Educational only — not medical advice

Deep dive

Full Epitalon review

A four-amino-acid synthetic peptide.

CompareResearch-gradeSafety