PEPTIDE
Verified Peptide ReviewLast reviewed: 28 March 2026

Compound Profile · GH Secretagogue

Hexarelin

Hexarelin is a hexapeptide GH secretagogue studied in research for GH release and muscle-building effects. It is not approved for human use.

LegalResearch onlyEvidenceEmergingHuman useNot approved
7.2/ 10

Peptide Score

Evidence

7.2

Safety

7.2

Regulatory

6.8

Transparency

7.2

Quick verdict

Potent GH release in research, but cortisol elevation is a notable concern. Less-studied selectivity profile than ipamorelin.

Reality check

What this isn't

  • Not approved for human use — research-only context
  • No regulator has approved human use
  • Evidence base is early — long-term data limited
  • Side-effect profile not fully characterised
  • Educational only — not medical advice

Deep dive

Full Hexarelin review

A six-amino-acid peptide GH secretagogue acting on the ghrelin/GHS-R.

Structurally related to other hexapeptide secretagogues but with distinct receptor kinetics.

CompareResearch-gradeSafety