PEPTIDE
Verified Peptide ReviewLast reviewed: 14 April 2026

Compound Profile · Cosmetic

SNAP-8

SNAP-8 is a synthetic octapeptide studied in topical cosmetic research for effects on muscle contractions and wrinkle formation.

LegalResearch onlyEvidenceEmergingHuman useNot approved
6.8/ 10

Peptide Score

Evidence

6.4

Safety

7.6

Regulatory

6.8

Transparency

6.8

Quick verdict

Topical cosmetic peptide with in vitro evidence for SNARE modulation. Human efficacy data are limited.

Reality check

What this isn't

  • Not approved for human use — research-only context
  • No regulator has approved human use
  • Evidence base is early — long-term data limited
  • Side-effect profile not fully characterised
  • Educational only — not medical advice

Deep dive

Full SNAP-8 review

An acetylated octapeptide derived from SNAP-25.

Studied topically for anti-wrinkle effects through modulation of muscle contraction.

CompareResearch-gradeSafety