PEPTIDE
Verified ComparisonLast updated: 19 April 2026

Hexarelin vs Ipamorelin

Both hexarelin and ipamorelin are GHS-R agonists used to stimulate GH release. Hexarelin is more potent but less selective; ipamorelin shows greater selectivity for GH secretion.

Compound A

Hexarelin

GH Secretagogue

Evidence
4.1/ 5
A−

Compound B

Ipamorelin

GH Secretagogue

Evidence
4.2/ 5
A−
Editor's note
Ipamorelin is more selective for GH; hexarelin has broader GHS-R activity.
CriterionHexarelinIpamorelin
MechanismGHS-R agonist (broader)GHS-R agonist (selective)
PotencyHighModerate-high
Selectivity for GH releaseModerateHigh
Prolactin elevationCan occurMinimal
Research literature discussionModerateExtensive

Frequently asked questions

Ipamorelin is more selective for GH secretion with minimal off-target effects.

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