PEPTIDE
Verified ComparisonLast updated: 23 March 2026

LR3 IGF1-Des vs IGF-1 LR3

Both are modified IGF-1 molecules designed for extended half-life and potency. LR3 IGF1-Des is a variant emphasizing local tissue effects.

Compound A

Des(1-3) IGF-1

Growth Hormone

Evidence
3.8/ 5
B+

Compound B

IGF-1 LR3

Growth Hormone

Evidence
4.1/ 5
A−
Editor's note
IGF-1 LR3 is more established; LR3 IGF1-Des offers localized action.
CriterionDes(1-3) IGF-1IGF-1 LR3
Modification typeLong-chain + Des(1-3)Long-chain (LR3)
Half-life extensionVery longVery long
Systemic vs localizedLocalized preferenceSystemic
Preclinical evidenceGrowingExtensive
Research popularityEmergingEstablished

Frequently asked questions

IGF-1 LR3 has more extensive literature; LR3 IGF1-Des is newer.